Shafaii Moghadam et al. (2020) contribute important new data on Late Cretaceous-Tertiary subduction- related magmatism in Iran, but their plate convergence model, wherein Neotethyan subduction begins in mid-Cretaceous time (c. 100 Ma), overlooks well established facts relating to the tectonic history of Neotethys, in regard to global plate reconstructions, paleolatitude data, the regional stratigraphy, geochronology and geochemistry, and metamorphic history. Based on their model, Neotethys subduction beneath Eurasia began at ~100 Ma, meaning that the Neotethys was spreading and bounded by opposing passive margins during Jurassic and Early Cretaceous time, for ~100 Ma prior to their proposed onset of Neotethyan convergence. Consequently, their subduction model contradicts (1) the Indian Ocean spreading history derived from magnetic anomalies; (2) continental paleolatitude data from paleomagnetism; (3) sedimentary and igneous evolution of the Mesozoic continental margins in Arabia and southern Asia, (4) the age and geochemistry of Jurassic igneous rocks in southernmost Eurasia; and (5) the preservation of Early to Middle Jurassic eclogite metamorphism and exhumation on the northern side of the Arabia-Eurasia suture. Reconciliation of each of these omissions and contradictions of their model would be welcome, and perhaps an advisory that readers may wish to evaluate their concept of Cretaceous subduction initiation with due circumspection.