Niki Tadayon

and 2 more

Dear Editor,We read the article by Salimi et al. on the endovascular management of post PCNL vascular injuries with great interest 1. In their study, the authors successfully diagnosed and treated post Percutaneous nephrolithotomy (PCNL) hematuria in 14 patients using angiography and subsequent embolization. They reported a 100% success rate, with ten patients having pseudoaneurysm (PA), four having arteriovenous fistula (AVF), and one having both subscapular hematoma and PA 1. The authors concluded that angiography is a safe and effective method for diagnosing etiology and treating post-PCNL hemorrhage.While we acknowledge the significance of the interventions and outcomes presented in this article, we believe further clarification on certain aspects is necessary. Firstly, it is crucial to understand the criteria used to determine the necessity of an invasive procedure such as angiography and coil embolization. The authors did not specify the threshold for significant hematuria that prompted the invasive intervention. Factors such as the number of units of packed red blood cells transfused, the presence of shock, or the duration of gross hematuria following the index PCNL procedure should be elucidated to provide a clearer context for their approach.Additionally, the authors attributed gross hematuria to PA or AVF in all cases. However, it is important to acknowledge that post-PCNL hematuria can have other causes and treatments, including infection, as reported by Dhangar and colleagues 2. Even in cases with vascular etiologies such as PA, other non-invasive alternatives, such as administration of tranexamic acid, have been reported by Kumar et al.3 and Feng et al. 4 as effective solutions.Considering the diversity in etiology and management options for post-PCNL hematuria, we propose that utilizing non-invasive investigations, such as computerized tomography (CT) angiogram, before proceeding to angiography, an invasive procedure, would be a reasonable approach. This could help in better patient selection for invasive procedures, potentially reducing the risk and cost associated with unnecessary interventions. This point would be clearer with a larger patient cohort.In conclusion, despite the benefits and precision of angiography, we suggest that it might be better for physicians to consider non-invasive utilities like CT angiograms as the first step of evaluation and also have a risk assessment for ordering invasive investigation until clear clinical and laboratory data indicate post-PCNL vascular injury needs angioembolization.

Pooria Nakhaei

and 10 more

Background: The introduction of the frozen elephant trunk (FET) technique for total arch replacement (TAR) has revolutionized the field of aortovascular surgery. However, although FET yields excellent results, the risk of certain complications requiring secondary intervention remains present, negating its one-step hybrid advantage over conventional techniques. This systematic review and meta-analysis sought to evaluate controversies regarding the incidence of FET-related complications, with a focus on aortic remodeling, distal stent-graft induced new entry (dSINE) and endoleak, in patients with type A aortic dissection (TAAD) and/or thoracic aortic aneurysm. Materials and methods: A comprehensive literature search was conducted using multiple electronic databases including EMBASE, Scopus, and PubMed/MEDLINE to identify evidence on TAR with FET in patients with TAAD and/or aneurysm. Studies published up until January 2022 were included, and after applying exclusion criteria, a total of 43 studies were extracted. Results: A total of 5068 patients who underwent FET procedure were included. The pooled estimates of dSINE and endoleak were 2% (95% CI 0.01-0.06, I 2 = 78%) and 3% (95% CI 0.01-0.11, I 2 = 89%), respectively. The pooled rate of secondary thoracic endovascular aortic repair (TEVAR) post-FET was 7% (95% CI 0.05-0.12, I 2 = 89%) whilst the pooled rate of false lumen thrombosis at the level of stent-graft was 91% (95% CI 0.75-0.97, I 2 = 92%). After subgroup analysis, heterogeneity for dSINE and endoleak resolved among European patients, where Thoraflex Hybrid and E-Vita stent-grafts were used (both I 2 = 0%). In addition, heterogeneity for secondary TEVAR after FET resolved among Asians receiving Cronus (I 2 = 15.1%) and Frozenix stent -grafts (I 2 = 1%). Conclusion: Our results showed that the FET procedure in patients with TAAD and/or aneurysm is associated with excellent results, with a particularly low incidence of dSINE and endoleak as well as highly favorable aortic remodeling. However the type of stent-graft and the study location were sources of heterogeneity, emphasizing the need for multicenter studies directly comparing FET grafts. Finally, Thoraflex Hybrid can be considered the primary FET device choice due to its superior results.