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Pulmonary artery aneurysm associated with a non-stenotic bicuspid pulmonic valve: a role for genetics?
  • Sophia Alexis,
  • Ismail El-Hamamsy,
  • Michael Robbins
Sophia Alexis

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Ismail El-Hamamsy
Mount Sinai School of Medicine
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Michael Robbins
Mount Sinai Doctors Forest Hills
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Background Bicuspid pulmonic valves are quite uncommon, being described in only 0.1% of donor hearts, while pulmonary artery aneurysms are even more rare, having been found in 8 out of 109,571 autopsies. This rarity makes it difficult to characterize the relationship between them. Materials & Methods We describe the case of a 66-year-old female who was found to have a bicuspid pulmonic valve and pulmonary artery aneurysm (5.1cm) on imaging by her cardiologist. Discussion & Conclusion This case raises the question of whether the association between bicuspid semilunar valve disease and vascular wall anomalies are more genetic or hemodynamic. Even on the aortic side, despite the robust association between bicuspid aortic valves and thoracic aortic aneurysms, the mechanism still remains unclear. In our patient there was no significant gradient across the bicuspid pulmonic valve, suggesting that hemodynamics are not the primum mobile of this association.
28 Jun 2021Submitted to Journal of Cardiac Surgery
01 Jul 2021Submission Checks Completed
01 Jul 2021Assigned to Editor
03 Jul 2021Reviewer(s) Assigned
15 Aug 2021Review(s) Completed, Editorial Evaluation Pending
17 Aug 2021Editorial Decision: Revise Minor
15 Sep 20211st Revision Received
15 Sep 2021Submission Checks Completed
15 Sep 2021Assigned to Editor
15 Sep 2021Reviewer(s) Assigned
24 Sep 2021Review(s) Completed, Editorial Evaluation Pending
25 Sep 2021Editorial Decision: Accept