MEDICATION DISCREPANCIES IDENTIFIED DURING MEDICATION RECONCILIATION IN
PATIENTS IN A MEDIUM-SIZED HOSPITAL
Abstract
Objective: To analyze the medication discrepancies (MD) in prescriptions
of patients during a medication reconciliation (MR) service at admission
to the Medical Unit. Methods: Cross-sectional study, carried out from
March 2021 to February 2022, in a medium-sized hospital. Patients aged
18 years or older and in continuous use of at least one medication at
the time of hospitalization were included. The first interview at the MR
service was preferably carried out within 24 hours to collect
sociodemographic data, health indicators, detailed information on home
pharmacotherapy. Data were analyzed using Stata 13.0 software. Pearson’s
chi-square test was performed for statistical analysis. The study was
approved by CEP/UFOP under number 4,845,642. Results: Of the 215
patients included, 115 were female, with a mean age of 68 ± 18 years.
The mean number of medications in use at the time of admission was 6±3.
Polypharmacy was identified in 128 patients. The variables age group
(p=0.005), polypharmacy (p<0.001), having Hypertension and/or
Diabetes Mellitus (p=0.001), hospitalization for infectious and
parasitic diseases (p<0.001) and diseases of the circulatory
system (p=0.040) are significantly related to the occurrence of at least
one DM. Medications used in Diabetes Mellitus (p<0.001),
Agents that act on the Renin-Angiotensin System (p=0.028), Lipid
Modifying Agents (p=0.026), Medications for Obstructive Airway Diseases
(p=0.001), general nutrients (p=0.005) and thyroid hormone medications
(p=0.002) were associated with unintentional DM Conclusion: It was
possible to identify a significant percentage of MD in the prescription
evaluated. Polypharmacy and age group were related to the occurrence of
MD