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Masanori Oshi
Public Documents
2
BRCA2 reversion mutation confers resistance to olaparib in breast cancer
Shinya Yamamoto
and 14 more
February 20, 2023
A 34-year-old woman with breast cancer and the BRCA2: p.Gln3047Ter was treated with olaparib. After tumor progression, cancer genomic profiling testing revealed the BRCA2 p.Gln3047Ter and p.Gln3047Tyr, with 48.9% and 0.37% allele frequency, respectively. These findings shed light on reversion mutation as a resistance mechanism to olaparib in breast cancer.
Granulomatous Mastitis in a Male Breast: A Case Report and Review of Literature
Kei KAWASHIMA
and 10 more
December 23, 2022
Granulomatous mastitis (GM) is a rare disease, particularly amongst men. Herein, we present a case of GM diagnosed in a 63-year-old male patient who showed reduction in the tumor size during 3 months of observation.