Determination of Antimicrobial and Antioxidant Activity of Syrups Used
for Upper Respiratory Tract Infections in Children This article is an
interdisciplinary study. It was to reveal that syrups with coughing and
septone and alkali used especially after the colds of children are in
two groups as chemical and plant-added syrups. The presence of
antioxidant antimicrobial and properties of these syrups, which are
widely used, and the effect of herbal syrups between chemical syrups. It
provides practical in
Abstract
The aim was to research the antimicrobial effects against clinically
significant bacterial and fungal organisms and antioxidant activities of
some syrups sold with and without prescriptions and commonly used for
upper respiratory tract infections in children. The antimicrobial
efficacy of 10 syrups, with five chemical-based and five herbal-based,
against nine bacteria and one yeast species was tested with the disc
diffusion method and data in the research were statistically analyzed.
Additionally, the antioxidant efficacy of the syrups was researched with
total phenolic content in addition to tests based on different methods.
This study found herbal-based syrups had mean activity (11 mm) that was
higher compared to chemical-based syrups (9.42 mm) according to results
obtained by measuring the inhibition diameters. Among all syrups, the
syrup containing Pelargonium sidoides root extract had highest activity
against all microorganisms. While the total phenolic content of a syrup
with chemical origin was higher than that of all other syrups, the
antioxidant activity of another syrup containing many herbal extracts at
the same time was considerably higher as a result of
2,2-diphenyl-1-picryl-hydrazyl-hydrate (DPPH) assay. Herbal-based syrups
have stronger antimicrobial efficacy compared to chemical-based syrups.
The strongest antimicrobial activity was in syrups with herbal-based
active material of Pelargonium sidoides root extract and thyme fluid
extract. The antioxidant activities of herbal syrups containing extracts
of different parts of herbal species such as thyme, licorice root,
echinacea, ginger, African geranium, barberry, and acerola were found to
be more effective according to all three methods tested.