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Associations between Male Gender, Body Size and Dimension of the Epiglottis
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  • Chih-Wei Sung,
  • Wai_Ho Chan,
  • Chih-Heng Chang,
  • Pei-Chuan Huang,
  • Wan-Ching Lien,
  • Wei-Tien Chang,
  • Chien-Hua Huang
Chih-Wei Sung
National Taiwan University Hospital Hsin-Chu Branch
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Wai_Ho Chan
Tan Tock Seng Hospital
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Chih-Heng Chang
National Taiwan University Hospital Jinshan Branch
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Pei-Chuan Huang
National Taiwan University Hospital
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Wan-Ching Lien
National Taiwan University Hospital
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Wei-Tien Chang
National Taiwan University Hospital
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Chien-Hua Huang
National Taiwan University Hospital
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Peer review status:UNDER REVIEW

30 Jun 2020Submitted to Clinical Otolaryngology
02 Jul 2020Assigned to Editor
02 Jul 2020Submission Checks Completed
05 Jul 2020Reviewer(s) Assigned

Abstract

Objective: This prospective observational study aims to measure the epiglottic thickness by ultrasonography (US) in healthy volunteers. Methods: Healthy adult volunteers were recruited from the National Taiwan University Hospital between October and November 2019. Exclusion criteria included preexisting airway diseases, neck tumors, and a history of neck operation. Epiglottic thickness was measured at the midpoint, right and left edges of the epiglottis. Age, sex, height, weight, and body mass index (BMI) were collected. The linear regression model was employed to identify parameters to be associated with the epiglottic thickness. Coefficients and 95% confidence intervals (CIs) were computed. The literature was also reviewed. Results: There were 124 Chinese adults and 63 were men. The average age was 32.5±10.4 years. The midpoint, right edge and left edge of the epiglottic thickness was 2.03±0.42 mm, 2.14±0.42 mm and 2.21±0.42 mm, respectively. Male gender (midpoint, coefficient, 0.38, 95% CI, 0.35-0.43; right edge, coefficient, 0.33, 95% CI, 0.31-0.35; left edge, coefficient, 0.31, 95% CI, 0.29-0.35) and BMI (midpoint, coefficient, 0.02, 95% CI, 0.019-0.021; right edge, coefficient, 0.02, 95% CI, 0.019-0.022; left edge, coefficient, 0.02, 95% CI, 0.018-0.022) were associated with the epiglottic thickness. The epiglottis was thinner in normal Chinese adults, compared with that in Americans in the literature. Conclusions: US allows the depiction and assessment of the epiglottis in healthy volunteers. Male gender and higher BMI are associated with a thicker epiglottis. Future studies are warranted to evaluate race differences in the dimension of the epiglottic thickness.