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Do Covid-19 patients needing ICU admission have worse 6 months follow up outcomes when compared with hospitalized non-ICU patients? A prospective cohort study
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  • suleyman yildirim,
  • Seher Susam,
  • Pınar Cimen,
  • Sena Yapicioglu,
  • Onur Sunecli,
  • Özlem Ediboglu,
  • Cenk Kirakli
suleyman yildirim
Doktor Suat Seren Gogus Hastaliklari ve Cerrahisi Egitim ve Arastirma Hastanesi
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Seher Susam
University of Health Sciences Turkey, Dr Suat Seren Chest Diseases and Chest Surgery Training and Research Hospital
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Pınar Cimen
University of Health Sciences Turkey, Dr Suat Seren Chest Diseases and Chest Surgery Training and Research Hospital
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Sena Yapicioglu
University of Health Sciences Turkey, Dr Suat Seren Chest Diseases and Chest Surgery Training and Research Hospital
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Onur Sunecli
University of Health Sciences Turkey, Dr Suat Seren Chest Diseases and Chest Surgery Training and Research Hospital
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Özlem Ediboglu
University of Health Sciences Turkey, Dr Suat Seren Chest Diseases and Chest Surgery Training and Research Hospital
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Cenk Kirakli
University of Health Sciences Turkey, Dr Suat Seren Chest Diseases and Chest Surgery Training and Research Hospital

Corresponding Author:[email protected]

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Abstract

Objectives Long-term outcomes of COVID-19 patients who discharge ICU are unclear. We investigated the effect of COVID-19 on lung structure, pulmonary functional, exercise capacity and quality of life in patients discharge from ICU and medical ward. Methods A prospective single-centre study conducted in PCR confirmed COVID-19 patients who has been discharged from University of Health Sciences, Dr. Suat Seren Chest Disease and Thoracic Surgery Teaching and Research Hospital between 15 January and 5 March 2021. Patients who followed up for more than 48 hours in ICU and more than 72 hours in medical ward were included the study. Computed tomography scores, pulmonary functional tests (PFT), 6-min walking distance and health related quality of life by SF-36 were compared between ICU and medical ward patients at 6 months after discharge. Results Seventy patients were included final analyses and 31 of them discharged from ICU. ICU patients had higher CT scores than non-ICU patients at admission (17 vs 11) and follow up visit (6 vs 0). Two-three of ICU patients had at least one abnormal finding at control CT. Advanced age (OR 1.08, 95% CI 1.02-1.15) and higher CT score at admission (OR 1.13, 95% CI 1.01-1.27) were risk factors for having radiological abnormalities at control CT. 90% of the patients discharged from the ICU had at least one persistent symptom. Conclusion A number of COVID-19 survivors could not fully recover after 6 months of hospital discharge. COVID-19 survivor needs to support therapies at recovery phase of the disease.