Development of network pharmacology in sepsis treatment
- fangling chen,
- maolin chen
Abstract
So far, sepsis is still a global disease and health problem facing
mankind. Due to the complexity of the pathophysiology and pathogenesis
of sepsis, the idea that a drug corresponds to a single target - a
single disease is no longer suitable for the treatment of complex
diseases such as sepsis. The application of network pharmacology to
explore the signal network relationship between diseases, targets, and
drugs has gradually become a new disease treatment methodology. This
effective treatment for disease targets can improve the effectiveness
and success of drug therapy, and it is possible to develop from the
current treatment of symptoms of complex diseases to the real cure of
complex diseases. This paper will discuss the application and discovery
of network pharmacology in the treatment of sepsis, to provide a certain
scientific theoretical basis for the subsequent basic and clinical
research of sepsis treatment.