Introduction
Good’s syndrome(GS), a rare acquired
immunodeficiency condition, first described by Dr. Robert Good in 1954,
is characterized by thymoma, hypogammaglobulinemia, and low peripheral
B‑lymphocyte count. GS tend to occur in individuals aged 40‑60 years,
resulting in increased risk of recurrent infections with kinds of
conditionally pathogenic bacteria, viruses, and fungi[1, 2]. Almost
half of GS patients suffer from chronic diarrhea due to opportunistic
infections, such as Salmonella spp. , Campylobacter.
jejuni , Clostridium difficile , andCytomegalovirus(CMV)[3-5]. CMV, a kind of encapsulated double-stranded DNA
β-herpesvirus, is a common virus that can infect human beings. CMV could
cause pneumonia, retinitis, encephalitis, and enteritis in GS
patients[4, 6-14].We will report a female patient with GS and
chronic diarrhea due to CMV infection and make a literature review of
related cases to conclude the characteristics of this condition so as to
decrease the misdiagnosis and delayed diagnosis and improve the clinical
diagnosis and prognosis of this rare disease.