Title: Icariin alleviates renal inflammation and
tubulointerstitial fibrosis via Nrf2-mediated attenuation of
mitochondrial damage
Nannan Ding1, Shanyue Sun2, Shuting
Zhou3, Zhimei Lv1*, Rong
Wang1*
1. Department of Nephrology, Shandong Provincial Hospital Affiliated to
Shandong First Medical University, Jinan, China.
2. Shandong Provincial Hospital Affiliated to Shandong First Medical
University, Jinan, China.
3. Department of Pathology, The First Affiliated Hospital of Shandong
First Medical University & Shandong Provincial Qianfoshan Hospital,
Jinan, China.
*Correspondence: Zhimei Lv and Rong Wang are joint corresponding
authors. E-mail: lvzhimei@email.sdu.edu.cn &
wangrong_sd@126.com.
Running title: The protective mechanism of icariin in CKD