Metabolites Unadjusted Unadjusted Unadjusted Adjusted
OR 95% CI (OR) p-value OR 95% CI (OR) p -value§
Lys-Ala-Leu-Glu 0.014 0.002–0.101 0.001 0.001 0.001–0.027 0.001
Ser-Phe-Ala 5.423 2.505–11.743 0.001 5.53 2.425–12.626 0.001
11-Dehydrocorticosterone 0.127 0.048–0.337 0.001 0.076 0.021–0.268 0.001
l-beta-Phenylalanine 0.488 0.260–0.914 0.025 0.437 0.209–0.915 0.028
N-acetyl-l-methionine 0.018 0.002–0.161 0.001 0.015 0.001–0.169– 0.001
3-Methylhippuric acid 1.647 1.164–2.332 0.001 1.778 1.172–2.698 0.007
α-Ketoglutaric Acid 11.819 2.770–50.424 0.001 24.23 3.732–157.343 0.001
3-Methylxanthine 0.162 0.051–0.513 0.002 0.205 0.059–0.717 0.013
7-Methylxanthine 0.223 0.082–0.609 0.003 0.268 0.091–0.792 0.017
Pro-His 0.09 0.019–0.440 0.003 0.053 0.008–0.364 0.003