Case history/Examination:
A 40-year-old woman, classified as Fitzpatrick skin type III (Figure 1)
and CRF presented with hypopigmentation affecting the hair. She reported
no other medical history and no occupational exposure to chemicals and
lacked a family history of similar conditions.
In March 2021, the patient was diagnosed with a CRF of unidentified
origin, subsequently necessitating thrice-weekly hemodialysis sessions
since the aforementioned year.
In March 2023, she started treatment with heptaminol for hypotension
issues, with no concurrent use of other medications.
In June 2023, three months following the commencement of the medication
and two years subsequent to the initiation of hemodialysis, the patient
presented with the onset of hair depigmentation, affecting the eyebrows,
eyelashes, pubic hair and body hair (Figures 2 to7). Before commencing
the therapy, the patient had naturally black hair, a fact corroborated
by archived photographs. She denied any use of hair dye or bleaching
agents. No hypopigmentation was evident on his skin, and her nails and
mucous membranes appeared normal.