Case history/Examination:
A 40-year-old woman, classified as Fitzpatrick skin type III (Figure 1) and CRF presented with hypopigmentation affecting the hair. She reported no other medical history and no occupational exposure to chemicals and lacked a family history of similar conditions.
In March 2021, the patient was diagnosed with a CRF of unidentified origin, subsequently necessitating thrice-weekly hemodialysis sessions since the aforementioned year.
In March 2023, she started treatment with heptaminol for hypotension issues, with no concurrent use of other medications.
In June 2023, three months following the commencement of the medication and two years subsequent to the initiation of hemodialysis, the patient presented with the onset of hair depigmentation, affecting the eyebrows, eyelashes, pubic hair and body hair (Figures 2 to7). Before commencing the therapy, the patient had naturally black hair, a fact corroborated by archived photographs. She denied any use of hair dye or bleaching agents. No hypopigmentation was evident on his skin, and her nails and mucous membranes appeared normal.