Introduction:
Since the beginning of recorded human history, addiction to addictive
substances has been a medical and social issue. [1]
Nucleus accumbens dopamine levels control drug self-administration,
which is carried out in order to sustain a desirable hedonistic level by
keeping nucleus accumbens dopamine within a particular raised range.
Chronic use of some classes of addictive medicines leads to the
development of tolerance to the sensation of
euphoria.[1]
Drug consumption during pregnancy carries a number of possible risks for
the developing fetus, and in order to improve the health of both mother
and fetus, it is essential to recognize and address the issue by
understanding the effects of substance misuse during pregnancy on both
parties.[2]
The effects of drug usage during pregnancy differ according to the drug,
the dosage, and the duration of exposure period. Using illegal drugs
increases the risk of low
birthweight, premature delivery, abruption of the placenta, and
cognitive decline.[3]
The unique case that we discuss in this study involves a young pregnant
lady who used drugs both before and during her pregnancy, including
(Tramadol, Methamphetamine, Pregabalin and Chloral hydrate) which
resulted many complications that led to fetal malformations and fetal
death after delivery.