IgE quantification
Patients’ sera were applied
individually to the research version of the ALEX2Allergy Explorer (MacroArray Diagnostics). Total and allergen-specific
IgE were quantified as described previously.16 Values
above 0.3 kU/L were considered positive.
Statistical analysis
The statistical analyses were performed using GraphPad Prism 9 (San
Diego, CA), IBM SPSS Statistics 26 (Armonk, NY),
R programming language and RStudio
(Boston, MA), as explained in supplementary material.