3.1 Power calculation and F statistics
We calculated the power values and F statistics of included GWAS studies
to evaluate whether our sample size was enough to explore the causal
effect between BW and cancer risk. According to the previous articles
and our meta-analysis reporting the odds ratio (OR) of each cancer52 and the interpretation of instrumental variables to
BW, our study had an adequate statistical power (>80%) for
statistical calculation. Our F statistics were range from 4802.59 to
81695.06 which meant that there was no evidence of weak instrument bias
in our MR study. (Table 1)