Figure 4. Forest plot of the pooled diagnostic sensitivity and specificity of F. nucleatum , B. fragilis and E. coli for 5-FU resistance of colorectal cancer. CI: Confidence interval. TP: True Positive; FN: False Negative; FP: False Positive; TN: True Negative; F. nucleatum : Fusobacterium nucleatum ; B. fragilis : Bacteroides fragilis ; E. coli :Escherichia coli .