Network meta-analysis
The result of network meta-analysis was shown in figure 4.
The final network effect showed
that the comparisons with a statistically different including
Varenicline vs Placebo (OR=4.90,
95%CI [1.77,13.55]), Varenicline vs Naltrexone (OR=3.50, 95%CI
[1.13,11.06]), and Varenicline vs Bupropion (OR=3.32, 95%CI
[1.03,10.74]). This signified that compared with placebo,
Naltrexone, and Bupropion,
Varenicline had an evident
superiority in quitting smoking. The comparison between any other
interventions did not show a significant difference.