Funding
This work was supported by grants from the Cyrus Tang Foundation [419600-11102], the China Medical Board (CMB) Collaborating Program [12-108 and 15-216], and the National Key Research and Development Plan [2018YFC1002700 and 2018YFC1002702]. SZ is funded by the Cyrus Tang Foundation (http://www. tangfoundation.org/), CMB Collaborating Program (https://chinamedicalboard.org/), and Hsun K.Chou Fund of Zhejiang University Education Foundation [419600-11107]. XZ works on a project that is supported by the National Key Research and Development Plan. The funders had no role in the study design, data collection and analysis, decision to publish, or preparation of the manuscript.