Serum biomarkers of inflammation
There were no differences for patients treated with nitazoxanide and placebo in the levels of C-reactive protein (SMD -0.11; 95% CI -0.63 to 0.40; I2 = 69%; p = 0.67), IL-6 (SMD -0.21; 95% CI -0.74 to 0.32; I2 = 70%; p = 0.43), and IL-8 (SMD 0.15; 95% CI -0.21 to 0.50; I2 = 44%; p = 0.42).