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\begin{document}

\title{Identified and Characteristics Analysis of Drug-related Problems:
Pharmaceutical Care to Cardiovascular Patients in china}



\author[1]{Xiaoyi Guo}%
\author[2]{Jianchun Li}%
\author[1]{Jianman Guo}%
\author[1]{Lixia Zhao}%
\author[1]{Anchang Liu}%
\affil[1]{Shandong University Qilu Hospital}%
\affil[2]{Shandong University}%


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  \date{May 22, 2024}


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\begin{abstract}
Aim: Cardiovascular patients have a high risk for Drug-related
problems(DRPs) , howevre studies the prevalence and risk factor for
these patients in china are still unkown.This study was conducted to
identify characteristics and risk factors associated with DRPs of
cardiovascular patients in China, and assess the effectiveness of
pharmaceutical practice. Methods:This was a retrospective study in a
cardiology department of an academic teaching hospital for 12 months. A
total of 1729 patients were enrolled. Pharmaceutical care was
implemented by a pharmacy team. Drug-related problems were categorized
by the Pharmaceutical Care Network Europe(PCNE) classification V9.1.
Main outcome measure were the prevalence, characteristics and risk
factors of drug-related problems. Results: During this study, 203 DRPs
were found in 152(8.8\%) patients,204 intervention, the success rate of
intervention was 99.0\%. Hospitalized days [?] 8.5(OR=1.925,95\%
CI:1.363-2.717) had a better sensitivity and specificity in predicting
the occurrence of drug-related problems, compared with patient age and
number of concomitant diseases. The most common type of drug-related
problems was ``Effect of drug treatment not optimal''( 34.5\%) ,
``patient transfer related'' was the primary cause of drug-related
problems (35.3\%). Among the top medications associated with
drug-related problems were Auxiliary medications (20.2\%) followed by
antianginal medications (17.2\%) , Antiplatelet agents (11.8\%), and
\selectlanguage{greek}β-\selectlanguage{english}Adrenergic receptor antagonists (11.8\%). Conclusion: Drug-related
problems are relatively common in hospitalized cardiovascular patients
in China, ``patient transfer related'' is the primary cause and
``Hospitalized days'' is the major risk factors for these patients.
Pharmacist intervention can identify and resolve pertinent drug-related
problems to optimize medication therapy.%
\end{abstract}%



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