Interpretation
For families with induced labor due to congenital abnormalities revealed
by ultrasound and recurrent miscarriages, they will do whatever it takes
to seek an examination to determine the cause, and genetic testing has
also become a growing concern for them. The detection rate of
chromosomal abnormalities by karyotype analysis is 50%. With the
application of chromosomal microarray analysis (CMA), the detection
frequency of chromosomal abnormalities has increased by 3%-5%,26but there are still 30%-50% miscarriages with
unknown causes. When karyotype and chromosomal microarray analysis do
not reveal the cause of abortion, families and clinicians who have
miscarried expect to be able to identify the cause.