Interpretation
For families with induced labor due to congenital abnormalities revealed by ultrasound and recurrent miscarriages, they will do whatever it takes to seek an examination to determine the cause, and genetic testing has also become a growing concern for them. The detection rate of chromosomal abnormalities by karyotype analysis is 50%. With the application of chromosomal microarray analysis (CMA), the detection frequency of chromosomal abnormalities has increased by 3%-5%,26but there are still 30%-50% miscarriages with unknown causes. When karyotype and chromosomal microarray analysis do not reveal the cause of abortion, families and clinicians who have miscarried expect to be able to identify the cause.