Characteristics of HLA-tested patients and allele frequency
The clinical characteristics of 11,988 patients with HLA testing are
summarized in Table II . Overall, 36.7% patients were female.
The indications for HLA genotyping were as follows: 39.7% for kidney
transplantation, 15.8% for bone marrow transplantation, 9.2% for liver
transplantation, 1.8% for donors, 1.2% for lung transplantation, 0.4%
for multiple organ transplantation, 0.3% for heart transplantation, and
0.7% for other transplantations.
There were changes to the HLA testing methods over the 10-year study
duration, and different testing methods were used depending on the
transplanted organ. In total, 11,929 (99.5%) patients underwent HLA-B
typing, whereas HLA-DQB1 typing was performed least with the frequency
of 20.5% (Table II ).