Reducing severe cutaneous adverse and type B adverse drug reactions using pre-stored HLA genotypes
Running title: Preemptive HLA typing and adverse drug reactions
Kye Hwa Lee1, Kang Dong Yun2 · Hyun Hwa Kim2 · Yi Jun Kim3· Hyo Jung Kim4 · Ju Han Kim4 · Eun Young Song5, James Yun MD6,7, Hye-Ryun Kang2,8*
1Department of Information Medicine, Asan Medical Center, Seoul 05505, South Korea
2Drug Safety Center, Seoul National University Hospital, Seoul 03080, South Korea
3Institute of Convergence Medicine, Ewha Womans University Mokdong Hospital 07984, Seoul, Korea
4Seoul National University Biomedical Informatics and Systems Biomedical Informatics Research Center, Division of Biomedical Informatics, Seoul National University College of Medicine, Seoul 03080, South Korea
5Department of Molecular Medicine and Biopharmaceutical Sciences, Graduate School of Convergence Science and Technology and College of Medicine, Medical Research Center, Seoul National University, Seoul 03082, South Korea
6Department of Immunology and Rheumatology, Nepean Hospital, Sydney, Australia
7 Faculty of Medicine and Health, the University of Sydney, Sydney, Australia
8Institute of Allergy and Clinical Immunology, Seoul National University Medical Research Center, Seoul National University College of Medicine, Seoul 03080, South Korea
*Corresponding Author: Hye-Ryun Kang, MD, PhD
Department of Internal Medicine, Seoul National University Hospital, 101 Daehak-ro, Jongno-gu, Seoul 03080, South Korea
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