Conclusion
Within a large dataset of birth records from South China, we found that
COVID-19 lockdown was associated with a slightly shorter gestational
length and a moderately higher risk of PTB. Early and middle pregnancy
might be a more susceptible exposure window. The COVID-19 control
measures were implemented in many countries to reduce the spread of
infections and related morbidities. Meanwhile, the incidence of PTB
remains high globally, and options for the prevention of PTB are very
limited (44). Our findings suggest more attention and efforts are needed
to support pregnant women during the lockdown, particularly for those
with previous PTB as they are more susceptible (45). Health
professionals should make appropriate and timely treatment decisions for
pregnant women during the lockdown.