Results
The study group analyzed 110 patients (14 males and 96 females) with
SLE, with a female-to-male ratio of 8.8 to 1.2, and a mean age of 38.63
years with a standard deviation of 10.15 (mean age in males and females
14, respectively). 36 years with standard deviation of 7.84 years and
38.99 years with standard deviation of 10.43 years) No statistically
significant difference (Mann-Whitney test) was observed between the two
groups (P = 0.317). The mean age of onset of disease in the studied
patients was 32.57 years with a standard deviation of 10.92 (mean age of
onset of disease in men and women was 27.43 years with a standard
deviation of 10.87 years and 33.32 years with a standard deviation of
10.78), It was a year. There was no statistically significant difference
(Mann-Whitney test) between the two groups (P = 0.054).
According to Table 1, the highest clinical manifestation was related to
arthritis, in which 80 patients (72.7%) had this symptom, followed by
Maral Rush with 60.9%, oral ulcer with 31.8, renal disorders with 13.6
and the lowest observed symptoms, respectively. It was discoid in which
there were 5 patients (4.5%) and also according to Table 2, the highest
prevalence of antibodies was related to Anti Ds-DNA test in which 52
patients (47.3%) were positive and the lowest was related to Jo-1 (Jo),
PCNA (PCNA), Histones (H1) and Ribosomal-P-protein (RIB) in which only
one person (0.9%) was positive. The results of the Scl-70 (Scl), PM-Scl
100 (PM100) and Centromere B (CB) tests were also negative. There was no
significant relationship (chi-square test and Fisher’s exact test)
between age, onset age and sex with symptoms of Marar rash, discoid,
oral ulcer, nephritis and arthritis. Only a significant correlation
(Chi-square test) was observed between the clinical manifestations of
Marar rash and Oral Ulcer with the result of Anti-Ds DNA test (P-Value
<0.05). The results obtained from the logistic regression
model show that none of these variables age, sex, malar rash, discoid,
oral ulcer, nephritis and arthritis have a significant effect on the
result Anti -U1RNP / Sm (RNP / Sm) , Anti RO-52 recombinant , Anti -La /
SS , Anti-SM do not have (P> 0.05). Only the age of onset
of the disease has a significant effect on SSA-Ro 60 (60kDa) (SSA) and
Anti-Ds DNA tests, namly on average, the chance of a positive test
result increases by about 25% every year, respectively ( P = 0.020 , OR
= 1.246, CI: 1.036-1.499) and increases by about 16% (P = 0.015 , OR =
1.165, CI: 1.030-1.317) for both tests .There was no significant
relationship between the age of onset and other test results