Biochemical Changes in ABCD1- Mice
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Reduced VLCFA levels in brain and spinal cord
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Reduced VLCFA levels in various tissues and CNS
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Normalize oxidative stress,
Prevent mitochondria depletion
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Restore redox homeostasis,
stimulate mitochondrial biogenesis
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Reduce oxidative damages,
Prevent mitochondria depletion
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Normalize ER stress
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Restore Autophagy,
prevent accumulation of oxidized proteins
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