Figure Titles and Legends
Fig. 1 , Characteristics of ABCD1- rabbit model. (a). Plasma C26:0/C22:0 ratio in ABCD1- mutated rabbits. All three rabbits have 4 to 4.5-fold increase compared to a wild type rabbit with the same sex and age. (Data are presented as mean ± SD. ***, p=0.0001 vs. WT, significant difference was analyzed by one-way ANOVA followed by Dunnett’s test). (b). Representative T2-weighted MRI scans for a 21-month-old ABCD1- mutated rabbit brain. No abnormalities including demyelination in the interested regions, the corpus callosum (top) and periventricular white matter (bottom) were found in the brain.
Fig. 2 , Common and different phenotypes of ABCD1 deficiency between human being and mouse.