Biological characteristics
Elevated IgE, tryptase and eosinophil levels were documented in 4, 1 and 2 cases, respectively. None had abnormal TSH levels, anti-thyroperoxydase or anti-thyroglobulin antibodies.
Discriminating features between “probable ACEi-AE” and“probable histaminergic AE” patients at baseline
As to better identify clinical features that could help discriminating between the 2 AE mechanisms at referral, baseline characteristics of probable ACEi-AE patients were compared to those of probable histaminergic AE patients.
There was no statistically significant difference between the 2 groups. Notably, classical histaminergic features such as evening onset and duration < 24h were not significantly different between probable ACEi-AE patients and probable histaminergic AE patients.