3 RESULTS
A total of 569 singleton pregnancies were enrolled in our study, in
which 39 cases were FGR, 57 were SGA and 473 were normal singleton
pregnancies. The maternal clinical and neonates characteristics among
the three groups are presented in Table 1. The maternal height in SGA
group is shortest among the three groups. The maternal height in SGA
group was significantly shorter than that in the AGA group (P <
0.001), however, no significant differences were observed AGA group and
FGR group or between FGR group and SGA group (P ≥ 0.05). No
significant differences in maternal age, gravida, parity and APO were
observed among the three groups (P ≥ 0.05).
The parameters of UA velocities among the three groups are presented in
Table 2. The UA velocities parameters were decreased with the severity
of growth restriction. The UA-TAMXV and UA-PSV were reduced successively
in AGA, SGA and FGR ( all P < 0.05). Multivariate logistic
regression analysis suggested that the maternal height was predictive of
SGA (P = 0.001) (Table 3). However, all of the UA velocities
parameters were not independent predicting factors of SGA (P ≥
0.05). The UA-TAMXV was an independent predicting factor of FGR
(P = 0.029) (Table 4). However, there was no significant
correlation between maternal height and FGR (P ≥ 0.05). As showed
by the receiver operating characteristic (ROC) curves, the UA-TAMXV had
moderate predictive value for FGR, with an area under the ROC curve of
0.821 [95% confidence interval (CI): 0.785-0.853], with sensitivity
of 74.40% as well as specificity of 77.60%, respectively (Figure 1).