Conclusion
The objective of this study was to determine the association between circulatory levels of sHLA-G in pregnant mothers and SGA births. No difference was observed in the trajectory of sHLA-G during the period of pregnancy in mothers delivering SGA as compared to those delivering AGA. However, a trend towards higher sHLA-G levels at first trimester was observed in mothers delivering SGA, which can be explored further in studies with a larger sample size. sHLA-G levels combined with clinical and/or imaging (as seen in the ultrasound) risk factors could be used to build predictive models for early prediction of SGA births. Early prediction, proper management, and timely intervention of pregnancies that could result in SGA, may help in decreasing the mortality and morbidity in SGA neonates.