Funding
This work was supported by the National Natural Science Foundation of China(82205054), Anhui Province Key Laboratory of Modern Chinese Medicine Department of Internal Medicine Application Foundation Research and Development (2021AKLMCM002), Key Project of Natural Science Foundation of Anhui Province for College Scholar (KJ2021A0558), Key laboratory opening project of the ministry of education of Xinan Medical Science (2020XAYX08), Construction project of Jian Liu studio of TCM in Anhui province (secretary of development of traditional Chinese medicine [2018] no. 11), The 12th batch of ”115” innovation team in Anhui province (no. 1 [2019] of anhui talent office).
Authors Contribution
HD, LJ, and WY contributed to the study design. HD, FYY, and XD contributed to data analysis, wrote the first draft, and revised the manuscript. ZWD, WL and LY contributed to the specimen and date collection. LJ revised the manuscript critically for important intellectual content. All authors reviewed and accepted the content of the final manuscript.