Inflammatory cells Score 1 damage Score 2
Normal 0 normal 0
Scattered 1 minimal inflammation and colonic crypt hyperplasia 1
Increased 2 mild colonic crypt hyperplasia with or without focal invasion of the epithelium 2
Confluence 3 obvious colonic crypt hyperplasia, invasion of the epithelium, and goblet cell depletion 3
Transmural extension 4 extensive mucosal damage and extension to deeper structures of the bowel wall 4