Figure 2 . HE staining showed moderate acute and chronic
inflammation in the appendiceal orifice mucosa, accompanied by acute
cryptitis. A, 100x magnification; B, 200x magnification.
Considering the patient’s clinical history and endoscopic findings,
ulcerative colitis was suspected, and the patient was initiated on a
daily oral dose of 3g mesalazine. The patient reported gradual relief
from abdominal pain, and his bowel movements became regular and formed.
A follow-up colonoscopy in May 2020 showed improvement in the appearance
of the ulcers at the appendiceal orifice, with scattered areas of
congestion and erosion but no significant ulcer formation
(Figure 3 ). Biopsy results indicated severe acute and chronic
mucosal inflammation with erosions, interstitial eosinophilic
infiltrates, and focal granuloma formation. The patient, feeling
significantly improved, discontinued the medication on his own.