Figure 2 . HE staining showed moderate acute and chronic inflammation in the appendiceal orifice mucosa, accompanied by acute cryptitis. A, 100x magnification; B, 200x magnification.
Considering the patient’s clinical history and endoscopic findings, ulcerative colitis was suspected, and the patient was initiated on a daily oral dose of 3g mesalazine. The patient reported gradual relief from abdominal pain, and his bowel movements became regular and formed. A follow-up colonoscopy in May 2020 showed improvement in the appearance of the ulcers at the appendiceal orifice, with scattered areas of congestion and erosion but no significant ulcer formation (Figure 3 ). Biopsy results indicated severe acute and chronic mucosal inflammation with erosions, interstitial eosinophilic infiltrates, and focal granuloma formation. The patient, feeling significantly improved, discontinued the medication on his own.