2.1 Ethics Statement
Six-week-old specific pathogen-free (SPF) female BALB/c mice were purchased from Hangzhou Paisiao Biotechnology Co., Ltd., and all mice were in good health. Animal studies were conducted in strict accordance with the recommendations of the Institutional Animal Care and Use Committee (IACUC), and the animal protocols were approved by the Animal Experimentation Ethics Committee of the School of Medicine, Hangzhou City University.