Pathological structure under microscope
The surface of the tumor was the duodenal mucosa, with columnar brush
border cells, scattered goblet cells, Panes cells and the intrinsic
glands of the duodenal mucosa. There were focal infiltration of
lymphocytes and scattered eosinophils in the stroma of the lamina
propria, accompanied by hyperemia and edema, and telangiectasis. The
duodenal glands showed adenomatous hyperplasia at the base of the lamina
propria and the submucosa, which were surrounded by mucosal smooth
muscle fibers and divided into lobules. The glandular epithelium was
well differentiated without atypia. At the base of the tumor, there were
proliferating collagen fibrous connective tissue.(Fig. 2)
The specific gastric and intestinal epithelial immunohistochemical
markers were further examined, such as MUC2, CD-X2, villin and AB-PAS
staining. The results suggested that the tumor originated from the
mucosa of the duodenum, rather than intestinal metaplasia of the gastric
mucosa.(Fig. 3)