Introduction:
Although vaccination is an important and effective method to overcome
the COVID-19 disease, flares or new onset of many auto-immune diseases
have been described (1). Optic neuritis (ON) presented by sudden visual
loss, and orbital pain. Many factors may play a role in its pathogenesis
like trauma, demyelination, infection, autoimmunity, and granulomatous
(2). Previous researches revealed that some vaccinations against
influenza, polio, tetanus, and others, may cause ON (3).
We present a case of bilateral ON, leading to blindness related to the
mRNA COVID-19 vaccination.