Introduction:
Although vaccination is an important and effective method to overcome the COVID-19 disease, flares or new onset of many auto-immune diseases have been described (1). Optic neuritis (ON) presented by sudden visual loss, and orbital pain. Many factors may play a role in its pathogenesis like trauma, demyelination, infection, autoimmunity, and granulomatous (2). Previous researches revealed that some vaccinations against influenza, polio, tetanus, and others, may cause ON (3).
We present a case of bilateral ON, leading to blindness related to the mRNA COVID-19 vaccination.