MRI image scanning
All patients received a double dose (0.2ml/kg) of gadobutrol intravenously (Bayer Pharmaceuticals, specifications: 7.5ml/ tube, 1.0mol/L), 3D-FLAIR sequence scan was performed after a 4-hour delay using a 3T MR Scanner (GE signa pioneer 3.0T) and matching 21-channel head coil.
Before the contrast agent is injected, whole-brain T2 FLAIR scan (TE 95ms, TR 9000ms, Slice Thickness 5mm, FOV 24*0.9, TI 2468ms, Matrix Size 256*256, Echo Train Length 22, Acceleration Factor 1, Scan Time 1 min and 57 sec), inner ear scanning 3D FIESTA C Shim (TE 95ms, TR 6.6ms, Acceleration Factor 2, TI 3.1ms, Matrix Size 256*256, FOV 18*1, Slice Thickness 0.8mm, Scan Time 3 min and 37 sec) were performed. After an injection of gadolinium, 3D-FLAIR sequence scan (TE 189ms, TR 9000ms, Acceleration Factor 4, TI 2134ms, Slice Thickness 1mm, FOV 22*0.8, Matrix Size 320*320, Echo Train Length 180, Scan Time 10 min and 52 sec) was performed.