Figure 10. (A) Confocal laser scanning microscopy images of intracellular tracking of HBPSi-Apt@DOX. (B) pH and GSH dual-responsive DOX release of HBPSi-Apt@DOX. Reproduced with permission: Copyright 2023, American Chemical Society.[47] Schematic representation of ibuprofen loading (C) and the pH-controlled release (D) process of HBPSi-OA. Reproduced with permission: Copyright 2021, John Wiley and Sons.[45] (E) Schematic illustration of the in vivo drug release behavior of HBPSi-Apt@DOX. (F) In vivo fluorescence imaging of tumor-bearing mouse after injection of HBPSi-Apt@DOX. Histological analysis of tumor tissues (G) and flow cytometric dot plots (H) of tumor cells harvested from control and experimental groups. Reproduced with permission: Copyright 2022, Elsevier.[39]