Benign esophageal strictures using different endoscopic therapy is considered safe and effective for both short and long-term relief of dysphagia. endoscopic therapy, rather than surgery, has therefore been suggested as the primary therapy for most of these patients. The reported experience is mostly in patients with peptic strictures and there is little information on the efficacy and safety of different endoscopic therapy in patients with CES. Due to this lack of formal criteria, we are still unable to clarify how to choose the optimal endoscopic therapy method based on the situation of patients with benign esophageal strictures. many scholars suggested that the decision to select the type of endoscopic therapy is based on the assessment of stricture (simple vs complex), length and distal extent of the stricture, and the experience of the endoscopist[14]. Here, We describe first the case of a patient who ingested sodium hydroxide and consequently presented with CES, moreover, he was treated with multiple endoscopic methods. Since the esophageal strictures were located in the upper and the high risk of surgery, the patient chose endoscopic therapies. During the 6-year period, By comparing the remission time of these 4 endoscopic therapies, we found that ERI had the longest remission time, and the shortest was oral hormone, and the remission time continued to lengthen as the number of therapies increased, besides the therapeutic efficacy became more and more favorable.