Acknowledgments
The authors thank the iExplore animal facility (IGF, Montpellier) and
the Arpege platform (IGF, Montpellier) for the use of plate reader
fluorimeter for cell-population BRET and FRET assay. The authors thank
Philippe Marin, Jean-Philippe Pin, Laurent Prézeau, Charlotte Avet and
Michel Bouvier for providing biosensors and helpful discussions. We are
grateful to Charlotte Sarre for the mGlu5 receptor graphic design. This
work was supported by the Agence Nationale de la Recherche (JP,
ANR-22-CE16-0013 LEARN) and the European Research Council (ERC) under
the European Union’s Horizon 2020 research and innovation programme (JP,
grant agreement No. 646788 VERTICAL CITY).