Statistical analysis
Group measures are numerically expressed as mean ± SEM. The violin plots show the median, mean, first, and third quartiles. All statistical comparisons were performed between control values and those obtained from MK-801-treated animals, following the guidelines on experimental design and analysis in pharmacology (Curtis et al., 2018). The normality distribution of data was validated with the Kolmogorov–Smirnov test (P  = 0.05). No outliers were removed from the data. The comparability among experimental conditions was assessed by two-tailed paired (or unpaired) Student’s t-test, Mann-Whitney test, Wilcoxon test, Kruskal-Wallis test, or two-way repeated-measures (RM) analysis of variance (ANOVA), as appropriate. The Holm–Šidák post-hoc or Dunn’s post-hoc test was used for multiple comparisons among experimental groups, only when F achieved minimal statistical significance. For all the experiments, data were considered significant if P  < 0.05.