References
Arnold, O.H. (1999). Schizophrenia – A Disturbance of Signal
Interaction between the Entorhinal Cortex and the Dentate Gyrus? The
Contribution of Experimental Dibenamine Psychosis to the Pathogenesis of
Schizophrenia: A Hypothesis. Neuropsychobiology 40: 21–32.
Behrendt, R.P. (2016). Hallucinatory experience as aberrant event memory
formation: Implications for the pathophysiology of schizophrenia. Prog.
Neuro-Psychopharmacology Biol. Psychiatry 71: 203–209.
Chance, F.S., Nelson, S.B., and Abbott, L.F. (1998). Synaptic Depression
and the Temporal Response Characteristics of V1 Cells. J. Neurosci. 18:
4785–4799.
Colgin, L.L. (2016). Rhythms of the hippocampal network. Nat. Rev.
Neurosci. 17: 239–249.
Collitti-Klausnitzer, J., Hagena, H., Dubovyk, V., and Manahan-Vaughan,
D. (2021). Preferential frequency-dependent induction of synaptic
depression by the lateral perforant path and of synaptic potentiation by
the medial perforant path inputs to the dentate gyrus. Hippocampus 31:
957–981.
Curtis, M.J., Alexander, S., Cirino, G., Docherty, J.R., George, C.H.,
Giembycz, M.A., et al. (2018). Experimental design and analysis and
their reporting II: updated and simplified guidance for authors and peer
reviewers. Br. J. Pharmacol. 175: 987–993.
Deshmukh, S.S., Yoganarasimha, D., Voicu, H., and Knierim, J.J. (2010).
Theta Modulation in the Medial and the Lateral Entorhinal Cortices. J.
Neurophysiol. 104: 994–1006.
Du, H., Kwon, I.K., and Kim, J. (2013). Neuregulin-1 Impairs the
Long-term Depression of Hippocampal Inhibitory Synapses by Facilitating
the Degradation of Endocannabinoid 2-AG. J. Neurosci. 33: 15022–15031.
Dudek, S.M., and Bear, M.F. (1992). Homosynaptic long-term depression in
area CA1 of hippocampus and effects of N-methyl-D-aspartate receptor
blockade. Proc. Natl. Acad. Sci. 89: 4363–4367.
Egbujo, C.N., Sinclair, D., and Hahn, C.G. (2016). Dysregulations of
Synaptic Vesicle Trafficking in Schizophrenia. Curr. Psychiatry Rep. 18:
1–10.
Eichenbaum, H. (2004). Hippocampus: Cognitive Processes and Neural
Representations that Underlie Declarative Memory. Neuron 44: 109–120.
Engel, A.K., and Fries, P. (2010). Beta-band oscillations — signalling
the status quo? Curr. Opin. Neurobiol. 20: 156–165.
Faghihi, F., and Moustafa, A.A. (2015). A computational model of pattern
separation efficiency in the dentate gyrus with implications in
schizophrenia. Front. Syst. Neurosci. 9: 132405.
Fernández-Ruiz, A., Oliva, A., Soula, M., Rocha-Almeida, F., Nagy, G.A.,
Martin-Vazquez, G., et al. (2021). Gamma rhythm communication between
entorhinal cortex and dentate gyrus neuronal assemblies. Science (80).
372.
Fontaine, C.J., Gräfe, E.L., Pinar, C., Bonilla-Del Río, I., Grandes,
P., and Christie, B.R. (2020). Endocannabinoid receptors contribute
significantly to multiple forms of long-term depression in the rat
dentate gyrus. Learn. Mem. 27: 380–389.
Forsyth, J.K., and Lewis, D.A. (2017). Mapping the Consequences of
Impaired Synaptic Plasticity in Schizophrenia through Development: An
Integrative Model for Diverse Clinical Features. Trends Cogn. Sci. 21:
760–778.
Gloveli, T., Schmitz, D., Empson, R.M., and Heinemann, U. (1997).
Frequency-dependent information flow from the entorhinal cortex to the
hippocampus. J. Neurophysiol. 78: 3444–9.
Goethem, N.P. van, Hagen, B.T.J. van, and Prickaerts, J. (2018).
Assessing spatial pattern separation in rodents using the object pattern
separation task. Nat. Protoc. 13: 1763–1792.
Griego, E., Hernández-Frausto, M., Márquez, L.A., Lara-Valderrabano, L.,
López Rubalcava, C., and Galván, E.J. (2022). Activation of D1/D5
receptors ameliorates decreased intrinsic excitability of hippocampal
neurons induced by neonatal blockade of N-methyl-d-aspartate receptors.
Br. J. Pharmacol. 179: 1695–1715.
Hunsaker, M.R., Mooy, G.G., Swift, J.S., and Kesner, R.P. (2007).
Dissociations of the Medial and Lateral Perforant Path Projections Into
Dorsal DG, CA3, and CA1 for Spatial and Nonspatial (Visual Object)
Information Processing. Behav. Neurosci. 121: 742–750.
İmamoğlu, A., Wahlheim, C.N., Belger, A., and S. Giovanello, K. (2023).
Impaired mnemonic discrimination in children and adolescents at risk for
schizophrenia. Schizophrenia 9: 1–8.
Insel, T.R. (2010). Rethinking schizophrenia. Nature 468: 187–193.
Jeevakumar, V., Driskill, C., Paine, A., Sobhanian, M., Vakil, H.,
Morris, B., et al. (2015). Ketamine administration during the second
postnatal week induces enduring schizophrenia-like behavioral symptoms
and reduces parvalbumin expression in the medial prefrontal cortex of
adult mice. Behav. Brain Res. 282: 165–175.
Kaminitz, A., Barzilay, R., Segal, H., Taler, M., Offen, D., Gil-Ad, I.,
et al. (2014). Dominant negative DISC1 mutant mice display specific
social behaviour deficits and aberration in BDNF and cannabinoid
receptor expression. World J. Biol. Psychiatry 15: 76–82.
Kaya, M.C., Bulut, M., Kaplan, İ., and Gunes, M. (2019). Levels of
endocannabinoid metabolizing enzymes are not related with BDNF levels in
patients with schizophrenia: a case-controlled study. Psychiatry Clin.
Psychopharmacol. 29: 441–445.
Kjaerby, C., Hovelsø, N., Dalby, N.O., and Sotty, F. (2017).
Phencyclidine administration during neurodevelopment alters network
activity in prefrontal cortex and hippocampus in adult rats. J.
Neurophysiol. 118: 1002–1011.
Kraguljac, N.V., Carle, M., Frölich, M.A., Tran, S., Yassa, M.A., White,
D.M., et al. (2021). Mnemonic Discrimination Deficits in First-Episode
Psychosis and a Ketamine Model Suggest Dentate Gyrus Pathology Linked to
NMDA Receptor Hypofunction. Biol. Psychiatry Cogn. Neurosci.
Neuroimaging 6: 1185–1192.
Larson, J., and Munkácsy, E. (2015). Theta-burst LTP. Brain Res. 1621:
38–50.
Li, J.T., Zhao, Y.Y., Wang, H.L., Wang, X.D., Su, Y.A., and Si, T.M.
(2015). Long-term effects of neonatal exposure to MK-801 on recognition
memory and excitatory-inhibitory balance in rat hippocampus.
Neuroscience 308: 134–143.
Lilley, E., Stanford, S.C., Kendall, D.E., Alexander, S.P.H., Cirino,
G., Docherty, J.R., et al. (2020). ARRIVE 2.0 and the British Journal of
Pharmacology: Updated guidance for 2020. Br. J. Pharmacol. 177:
3611–3616.
Lopez-Rojas, J., Heine, M., and Kreutz, M.R. (2016). Plasticity of
intrinsic excitability in mature granule cells of the dentate gyrus.
Sci. Rep. 6: 21615.
Lopez-Rojas, J., Solis, C.A. de, Leroy, F., Kandel, E.R., and
Siegelbaum, S.A. (2022). A direct lateral entorhinal cortex to
hippocampal CA2 circuit conveys social information required for social
memory. Neuron 110: 1559-1572.e4.
Macek, T.A., Winder, D.G., Gereau IV, R.W., Ladd, C.O., and Conn, P.J.
(1996). Differential involvement of group II and group III mGluRs as
autoreceptors at lateral and medial perforant path synapses. J.
Neurophysiol. 76: 3798–3806.
Madar, A.D., Ewell, L.A., and Jones, M. V. (2019). Temporal pattern
separation in hippocampal neurons through multiplexed neural codes. PLOS
Comput. Biol. 15: e1006932.
Maher, B.J., and LoTurco, J.J. (2012). Disrupted-in-Schizophrenia
(DISC1) Functions Presynaptically at Glutamatergic Synapses. PLoS One 7:
e34053.
Márquez, L.A., Griego, E., López Rubalcava, C., and Galván, E.J. (2023).
NMDA receptor activity during postnatal development determines intrinsic
excitability and mossy fiber long-term potentiation of CA3 pyramidal
cells. Hippocampus 33: 906–921.
Nadel, L., Hupbach, A., Gomez, R., and Newman-Smith, K. (2012). Memory
formation, consolidation and transformation. Neurosci. Biobehav. Rev.
36: 1640–1645.
Nakahara, S., Turner, J.A., Calhoun, V.D., Lim, K.O., Mueller, B.,
Bustillo, J.R., et al. (2019). Dentate gyrus volume deficit in
schizophrenia. Psychol. Med. 1–11.
Nakao, K., Jeevakumar, V., Jiang, S.Z., Fujita, Y., Diaz, N.B., Annan,
C.A.P., et al. (2019). Schizophrenia-Like Dopamine Release Abnormalities
in a Mouse Model of NMDA Receptor Hypofunction. Schizophr. Bull. 45:
138–147.
Nakazawa, K., and Sapkota, K. (2020). The origin of NMDA receptor
hypofunction in schizophrenia. Pharmacol. Ther. 205: 107426.
Osborne, A.L., Solowij, N., Babic, I., Lum, J.S., Newell, K.A., Huang,
X.F., et al. (2019). Effect of cannabidiol on endocannabinoid,
glutamatergic and GABAergic signalling markers in male offspring of a
maternal immune activation (poly I:C) model relevant to schizophrenia.
Prog. Neuro-Psychopharmacology Biol. Psychiatry 95: 109666.
Peñasco, S., Rico-Barrio, I., Puente, N., Gómez-Urquijo, S.M., Fontaine,
C.J., Egaña-Huguet, J., et al. (2019). Endocannabinoid long-term
depression revealed at medial perforant path excitatory synapses in the
dentate gyrus. Neuropharmacology 153: 32–40.
Petersen, R.P., Moradpour, F., Eadie, B.D., Shin, J.D., Kannangara,
T.S., Delaney, K.R., et al. (2013). Electrophysiological identification
of medial and lateral perforant path inputs to the dentate gyrus.
Neuroscience 252: 154–68.
Prasad, K.M.R., Patel, A.R., Muddasani, S., Sweeney, J., and Keshavan,
M.S. (2004). The entorhinal cortex in first-episode psychotic disorders:
A structural magnetic resonance imaging study. Am. J. Psychiatry 161:
1612–1619.
Quintanilla, J., Jia, Y., Lauterborn, J.C., Pruess, B.S., Le, A.A., Cox,
C.D., et al. (2022). Novel types of frequency filtering in the lateral
perforant path projections to dentate gyrus. J. Physiol. 600:
3865–3896.
Ren, S. yu, Wang, Z. zhen, Zhang, Y., and Chen, N. hong (2020).
Potential application of endocannabinoid system agents in
neuropsychiatric and neurodegenerative diseases—focusing on FAAH/MAGL
inhibitors. Acta Pharmacol. Sin. 41: 1263–1271.
Saggu, S., Cannon, T.D., Jentsch, J.D., and Lavin, A. (2013). Potential
molecular mechanisms for decreased synaptic glutamate release in
dysbindin-1 mutant mice. Schizophr. Res. 146: 254–263.
Santoro, A. (2013). Reassessing pattern separation in the dentate gyrus.
Front. Behav. Neurosci. 7: 59930.
Scullin, C.S., and Partridge, L.D. (2012). Modulation by pregnenolone
sulfate of filtering properties in the hippocampal trisynaptic circuit.
Hippocampus 22: 2184–2198.
Segev, A., Yanagi, M., Scott, D., Southcott, S.A., Lister, J.M., Tan,
C., et al. (2020). Reduced GluN1 in mouse dentate gyrus is associated
with CA3 hyperactivity and psychosis-like behaviors. Mol. Psychiatry 25:
2832–2843.
Seshadri, S., Klaus, A., Winkowski, D.E., Kanold, P.O., and Plenz, D.
(2018). Altered avalanche dynamics in a developmental NMDAR hypofunction
model of cognitive impairment. Transl. Psychiatry 2017 81 8: 1–12.
Shigemoto, R., Kinoshita, A., Wada, E., Nomura, S., Ohishi, H., Takada,
M., et al. (1997). Differential Presynaptic Localization of Metabotropic
Glutamate Receptor Subtypes in the Rat Hippocampus. J. Neurosci. 17:
7503–7522.
Snyder, M.A., and Gao, W.J. (2013). NMDA hypofunction as a convergence
point for progression and symptoms of schizophrenia. Front. Cell.
Neurosci. 7: 1–12.
Stan, A.D., Ghose, S., Zhao, C., Hulsey, K., Mihalakos, P., Yanagi, M.,
et al. (2015). Magnetic resonance spectroscopy and tissue protein
concentrations together suggest lower glutamate signaling in dentate
gyrus in schizophrenia. Mol. Psychiatry 20: 433–439.
Szűcs, E., Dvorácskó, S., Tömböly, C., Büki, A., Kékesi, G., Horváth,
G., et al. (2016). Decreased CB receptor binding and cannabinoid
signaling in three brain regions of a rat model of schizophrenia.
Neurosci. Lett. 633: 87–93.
Tamminga, C.A., Stan, A.D., and Wagner, A.D. (2010). The hippocampal
formation in schizophrenia. Am. J. Psychiatry 167: 1178–93.
Vyleta, N.P., and Snyder, J.S. (2021). Prolonged development of
long-term potentiation at lateral entorhinal cortex synapses onto
adult-born neurons. PLoS One 16: e0253642.
Wang, W., Cox, B.M., Jia, Y., Le, A.A., Cox, C.D., Jung, K.M., et al.
(2018a). Treating a novel plasticity defect rescues episodic memory in
Fragile X model mice. Mol. Psychiatry 23: 1798–1806.
Wang, W., Jia, Y., Pham, D.T., Palmer, L.C., Jung, K.M., Cox, C.D., et
al. (2018b). Atypical Endocannabinoid Signaling Initiates a New Form of
Memory-Related Plasticity at a Cortical Input to Hippocampus. Cereb.
Cortex 28: 2253–2266.
Wang, W., Trieu, B.H., Palmer, L.C., Jia, Y., Pham, D.T., Jung, K.M., et
al. (2016). A Primary Cortical Input to Hippocampus Expresses a
Pathway-Specific and Endocannabinoid-Dependent Form of Long-Term
Potentiation. ENeuro 3: 10049–10053.
Welsby, P.J., Rowan, M.J., and Anwyl, R. (2009). Intracellular
mechanisms underlying the nicotinic enhancement of LTP in the rat
dentate gyrus. Eur. J. Neurosci. 29: 65–75.
Wu, J., Rowan, M.J., and Anwyl, R. (2006). Long-term potentiation is
mediated by multiple kinase cascades involving CaMKII or either PKA or
p42/44 MAPK in the adult rat dentate gyrus in vitro. J. Neurophysiol.
95: 3519–3527.
Yassa, M.A., and Stark, C.E.L. (2011). Pattern separation in the
hippocampus. Trends Neurosci. 34: 515–525.
Zanfirescu, A., Ungurianu, A., Mihai, D.P., Radulescu, D., and
Nitulescu, G.M. (2021). Targeting monoacylglycerol lipase in pursuit of
therapies for neurological and neurodegenerative diseases. Molecules 26:
5668.