Comparisons of Characteristics and Outcomes between Eligible and
Ineligible Patients, including those with CHADS2 score
<2
The baseline characteristics of eligible and ineligible patients,
including those with a CHADS2 score <2, are
presented in Table 5 . By putting low-risk patients back into
the ineligible group, it appears that there were more elderly patients
and patients with comorbidities in the eligible group, contrary to what
is shown in Table 3. Regarding outcomes, unlike the main analysis after
excluding patients with CHADS2 score <2, there
was no difference in stroke/SE risk between the groups, and the effect
of ineligibility on the risk of major bleeding was smaller and did not
reach statistical significance, although the risk of all-cause mortality
remained significantly higher in ineligible patients with an unadjusted
HR (95% CI) of 1.54 (1.29–1.83).