Outcome Eligible (n=4054) Eligible (n=4054) Ineligible & CHADS2 ≥ 2 (n=1709) Ineligible & CHADS2 ≥ 2 (n=1709) Hazard ratio (95% CI) P-value
No. of events Event rate, %/yr No. of events Event rate, %/yr
Major bleeding 224 1.83 163 3.67 2.00 (1.63–2.44) <0.0001
Stroke/SE 156 1.27 87 1.93 1.53 (1.17–1.98) 0.0016
Death from any cause 213 1.70 221 4.82 2.84 (2.36–3.43) <0.0001