Inclusion |
|
|
|
Age |
age ≥18 years |
7826 (100%) |
|
AF |
non-valvular atrial fibrillation |
7826 (100%) |
|
CHADS2
|
CHADS2 score ≥ 2 |
5763
(73.6%) |
2063 (26.4%) |
Exclusion |
|
|
|
Haemorrhage Risk |
History of major bleeding |
7547 (96.5%) |
279
(3.5%) |
Uncontrolled hypertension
|
SBP > 180mmHg or
DBP > 100mmHg
|
7701 (98.4%)
|
125 (1.6%)
|
Renal dysfunction |
Calculated CLCR < 30 mL/min |
7085
(90.5%) |
741 (9.5%) |
Hepatic function |
ALT or AST > 2 times the ULN or TBL ≥
1.5 times the ULN |
7608 (97.2%) |
218 (2.8%) |
Haemoglobin & platelet count |
Hgb < 10 g/dL or platelet
count < 100,000 cells/mL |
7324 (93.6%) |
502
(6.4%) |
Antiplatelet therapy |
Aspirin > 100 mg daily or Aspirin in
combination with thienopyridines |
7550 (96.5%) |
276
(3.5%) |
Anti-inflammatory agents |
chronic treatment with NSAIDs |
7513 (96%) |
313 (4.0%) |
Drug or alcohol dependence |
alcohol dependence |
7783 (99.5%) |
43
(0.5%) |
Overall |
|
4054 (51.8%) |
3772 (48.2%) |