3.6 Antimicrobial activity
In order to investigate whether the colored fractions from the fungiPenicillium gravinicasei P3SO332, Clonostachys roseaP2SO329 and Penicillium sclerotiorum P3SO224 showed antimicrobial
activity, using the broth microdilution method, the ethyl acetate
extract was analyzed for MIC determination. The color fractions
demonstrated antimicrobial activity against the tested microorganisms
(Table 1). The ethyl acetate extract from Clonostachys roseaP2SO329 had MIC value of 6.25 μg/mL against the strain E. coliATCC 25922 and a MIC of 12.5 µg/mL against S. aureus ATCC 25923.
Ethyl acetate extracts of the three isolates presented activity againstC. albicans ATCC 60193 (400 µg/mL).