Data sources and search strategies
Two independent investigators conducted a comprehensive assessment
followed by literature selection of relevant studies on Roxadustat for
cardiovascular and renal outcome events in patients with CKD published
before October 11, 2022 using the search engines PubMed, Embase database
and Cochrane Central Register of Controlled Trials, with the search
limited to English-language trials. Moreover, references of selected
trials as well as relevant previous meta-analyses were screened to
identify eligible trials that had not been identified by the database
searches. All articles identified by electronic and manual selects were
entered into EndNote X9. Duplicates were extracted and a database was
eventually prepared for further screening.