Discussion
. In the ATLANTIS study, Kraft et al found a strong correlation between
IOS-defined small airway dysfunction and asthma exacerbations(3).
Clinical symptoms of asthma and other obstructive lung diseases may be
attributed to long-term inflammation, increased resistance, narrowing,
and remodeling of small airways. Patients with congenital airway
anomalies exhibited elevated airway resistance with small airway
dysfunction as well. Airway stent implantation emerges as a promising
intervention, breaking the cycle of airway inflammation and enhancing
ventilation by counteracting dynamic airway collapse. Regular use of
inhaled corticosteroids may furthermore enhance small airway function
after stent implementation.
In our study, while limited by sample size, stent type, and follow-up
duration, offers evidence that airway stents can effectively address
respiratory symptoms and improve small airway function in congenital
airway anomalies. We have showcased the potential of impulse
oscillometry as a valuable post-stent implantation monitoring tool,
while also acknowledging the need for broader research endeavors.
Table 1. Demographic features of four patients with BONA stent
implantation