Discussion
. In the ATLANTIS study, Kraft et al found a strong correlation between IOS-defined small airway dysfunction and asthma exacerbations(3). Clinical symptoms of asthma and other obstructive lung diseases may be attributed to long-term inflammation, increased resistance, narrowing, and remodeling of small airways. Patients with congenital airway anomalies exhibited elevated airway resistance with small airway dysfunction as well. Airway stent implantation emerges as a promising intervention, breaking the cycle of airway inflammation and enhancing ventilation by counteracting dynamic airway collapse. Regular use of inhaled corticosteroids may furthermore enhance small airway function after stent implementation.
In our study, while limited by sample size, stent type, and follow-up duration, offers evidence that airway stents can effectively address respiratory symptoms and improve small airway function in congenital airway anomalies. We have showcased the potential of impulse oscillometry as a valuable post-stent implantation monitoring tool, while also acknowledging the need for broader research endeavors.
Table 1. Demographic features of four patients with BONA stent implantation