Overall Survival in RDW and D-Dimer
To examine the relationship between the RDW in DLBCL patients and OS, seven studies (1, 7, 37, 39-41, 43) with 1728 patients were included. Our findings showed that RDW levels had relationship with OS. The pooled analysis presented a significant association between increased RDW and adverse OS of the patients (HR Pooled= 2.01, 95% CI: 1.62-2.48, P value<0.01) (Table 1) (Plot 2). Examining the correlation between the D-Dimer and OS among the patients with DLBCL was performed by four studies (16, 19, 38, 42) with 1066 patients and D-Dimer levels correlated with poorer OS. The combined results also demonstrated that increased D-Dimer was associated with worse OS of the patients (HR Pooled= 2.30, 95% CI: 1.03-5.14, P value<0.05) (Plot 3).