2.5 Gene set enrichment analysis and protein-protein interaction
analysis
The identified protein list was used for pre-ranked Gene set enrichment
analysis (GSEA) using Hallmark (16) and KEGG database (17). The number
of permutations was set to 1000. Further, Cytoscape (Version 3.9.1) was
used to visualize the enriched pathways (18). For protein-protein
interaction analysis, significant protein list was used as input for
STRING (Version 11.5), keeping the interaction score to 0.4.