Associations Between Sexual Identity and HBV Infection
Sexual identity was classified into five groups, including no sex
(3.94%), heterosexual (88.43%), homosexual (0.83%), bisexual
(6.71%), and unclear (0.09%). In comparison to participants without
sexual behavior, the present study found that individuals who identified
as homosexual or bisexual had a significantly higher risk of HBV
infection across three models. Model 1 revealed that homosexual
individuals had an OR of 4.22 (95%CI: 1.99-8.94) and bisexual
individuals had an OR of 1.73 (95%CI: 1.15-2.59). Model 2 showed that
homosexual individuals had an OR of 5.75 (95%CI: 2.63-12.55) and
bisexual individuals had an OR of 2.23 (95%CI: 1.46-3.42). Model 3
demonstrated that homosexual individuals had an OR of 4.83 (95%CI:
1.86-12.57) and bisexual individuals had an OR of 1.78 (95%CI:
1.09-2.92). Notably, heterosexual individuals did not exhibit a
significant difference in HBV infection risk when compared to
participants without sexual behavior across all three models.
Upon stratification by gender, it was observed that among the men
population, individuals who identified as homosexual (OR=5.61, 95%CI:
2.53-12.48) or bisexual (OR=4.32, 95%CI: 2.51-7.44) exhibited a
increased risk of HBV infection in model 1, as compared to men without
sexual behavior. This trend persisted in models 2 and 3, where
homosexual (models 2: OR=7.96, 95%CI: 3.51-18.05; models 3: OR=5.89,
95%CI: 2.21-15.66) and bisexual (models 2: OR=4.45, 95%CI: 2.48-7.99;
models 3: OR=4.2, 95%CI: 2.2-8.03) individuals continued to demonstrate
a significantly elevated risk of HBV infection. Conversely, heterosexual
individuals did not exhibit a significant difference in HBV infection
risk as compared to men without sexual behavior across all three models.
However, in the women population, compared with women without sexual
behavior, whether heterosexual, or bisexual, no statistically
differences were observed across three models.