Associations Between Sexual Identity and HBV Infection
Sexual identity was classified into five groups, including no sex (3.94%), heterosexual (88.43%), homosexual (0.83%), bisexual (6.71%), and unclear (0.09%). In comparison to participants without sexual behavior, the present study found that individuals who identified as homosexual or bisexual had a significantly higher risk of HBV infection across three models. Model 1 revealed that homosexual individuals had an OR of 4.22 (95%CI: 1.99-8.94) and bisexual individuals had an OR of 1.73 (95%CI: 1.15-2.59). Model 2 showed that homosexual individuals had an OR of 5.75 (95%CI: 2.63-12.55) and bisexual individuals had an OR of 2.23 (95%CI: 1.46-3.42). Model 3 demonstrated that homosexual individuals had an OR of 4.83 (95%CI: 1.86-12.57) and bisexual individuals had an OR of 1.78 (95%CI: 1.09-2.92). Notably, heterosexual individuals did not exhibit a significant difference in HBV infection risk when compared to participants without sexual behavior across all three models.
Upon stratification by gender, it was observed that among the men population, individuals who identified as homosexual (OR=5.61, 95%CI: 2.53-12.48) or bisexual (OR=4.32, 95%CI: 2.51-7.44) exhibited a increased risk of HBV infection in model 1, as compared to men without sexual behavior. This trend persisted in models 2 and 3, where homosexual (models 2: OR=7.96, 95%CI: 3.51-18.05; models 3: OR=5.89, 95%CI: 2.21-15.66) and bisexual (models 2: OR=4.45, 95%CI: 2.48-7.99; models 3: OR=4.2, 95%CI: 2.2-8.03) individuals continued to demonstrate a significantly elevated risk of HBV infection. Conversely, heterosexual individuals did not exhibit a significant difference in HBV infection risk as compared to men without sexual behavior across all three models.
However, in the women population, compared with women without sexual behavior, whether heterosexual, or bisexual, no statistically differences were observed across three models.