Author contributions
S.M. conceived and directed the study; A.L.M. and S.V.C. performed the experiments; S.G. and T.K. performed the bioinformatics analysis; C.S.A. performed the mass spectrometry; A.L.M. and S.M. drafted and finalised the manuscript with inputs from other authors. A.L.M. prepared the figures; all authors read and approved the manuscript.