Treatment program
Azvudine Group: Azvudine (1 mg/tablet; Henan Real Technology Biological Co. Ltd.) 5 mg orally once daily for 5 days.
Paxlovid Group: Nirmatrelvir and ritonavir (150 and 100 mg tablets, respectively Pfizer), with a standard authorized dose of 300 mg and 100 mg, respectively (two nirmatrelvir tablets and one ritonavir tablet), every 12 h with or without food for 5 days; the real dose of paxlovid was adjusted based on the patient’s renal allograft function.
Group A+P: Azvudine orally for 3-5 days at 5 mg daily, subsequently switched to paxlovid if the disease worsened or the viral load increased, based on the standard regimen.