Author contribution
F.K.D. and P.C.L. designed and supervised the project. P.W.S. performed laboratory experiments and statistical analyses. P.W.S., P.C.L., and D.F.K. drafted the manuscript. J.T.C., M.X.L., and C.T.C. assisted with data interpretation, provided valuable feedback, and revised the manuscript. All authors have read and approved the final version of the manuscript.